Chiral β-arylamines exist in numerous biologically interesting natural products and therapeutic agents.They also serve as pivotal structural units for many active pharmaceutical ingredients.We have successfully developed a novel C2-symmetric P-chiral bisphosphorus ligands WingPhos with a deep and well-defined chiral pocket that have shown high efficiency in rhodium-catalyzed asymmetric hydrogenation of (E)-β-aryl-N-acetyl enamides, cyclic β-arylenamides, and heterocyclic β-arylenamides.A series of chiral β-arylisopropylamines, 2-aminotetralines, and 3-aminochromans can be synthesized in excellent ee values at high s/c ratios (up to 10,000 TON).