MiR-1182 attenuates gastric cancer proliferation and metastasis by targeting the open reading frame

来源 :The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议) | 被引量 : 0次 | 上传用户:qiukaifeng
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background hTERT is an ideal anticancer target because it is universally expressed in cancer cells and plays a crucial role in carcinogenesis.In our previous study, we demonstrated that over-expression of miR-1182 suppresses hTERT expression.However, the mechanism of how miR-1182 modulates hTERT has not yet been investigated.
其他文献
Aim Peroral endoscopic myotomy (POEM), the brand-new groundbreaking therapy, seems to be superior to the old treatments like pneumatic dilation and laparoscopic Hellers myotomy.In this randomized cont
会议
Background and aims Myosin light chain kinase (MLCK) plays a central role in the mechanisms of barrier dysfunction, and a lot of studies showed the intestinal barrier permeability increased in nonalco
会议
Aims Bromo adjacent homology domain 1 (BAHD1), which involved in category of epigenetics maintains homeostasis by promoting heterochromatin formation.Our study aimed to investigate the underlying mech
会议
Background and aim Differentiating between malignant and benign biliary lesions is critical in clinical practice but is difficult.The aim of this study is to systematically review Spyglass diagnostic
会议
Objective To investigate the clinical application of endoscopic ultrasonography in the diagnosis of common bile duct stones.Method 18 patients who get the abdominal pain, combined with the patients me
会议
Objective To explore the relationship of the changes of alphafetoprotein (AFP), serum ferritin(SF) and des-y-carboxy prothrombin (DCP) pre and post micro-invasive treatment for hepatocellular carcinom
会议
Objective Liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been demonstrated to reduce hepatic steatosis.However, the mechanism of the lipid-lowering effect of liraglutide in the liver rem
会议
Objective Helicobacter pylori (H.pylori) maintains long-term persistence in the host and combats oxidative stress via diverse antioxidant proteins, which are expected to be relevant to bacterial-assoc
会议
Aims Epithelial mesenchymal transition plays an important role in metastasis of cancer.One of research has shown that another member of the GKN family, GKN1, can inhibit epithelial mesenchymal transit
会议
Background and aims Nowadays, there are few reports indicating whether early esophageal cancers with near-circumferential lesions are still appropriate for the ESD procedure.The aim of the present stu
会议