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  5. Bamboo Extract Reduces Interleukin 6 (IL-6) Overproduction under Lipotoxic Conditions through Inhibi

Bamboo Extract Reduces Interleukin 6 (IL-6) Overproduction under Lipotoxic Conditions through Inhibi

来源 :2011年第一届内分泌与代谢大会 | 被引量 : 0次 | 上传用户：julykoko
【摘 要】
：
Interleukin 6 (IL-6) is an inflammatory cytokine overexpressed in obese subjects contributing to the development of insulin resistance, type 2 diabetes, and cardiovascular diseases.This study investig
【作 者】
：
Jun Panee 
【机 构】
：
Department of Cell and Molecular Biology University of Hawaii USA
【出 处】
：
2011年第一届内分泌与代谢大会
【发表日期】
：
2011年3期
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论文部分内容阅读
　　Interleukin 6 (IL-6) is an inflammatory cytokine overexpressed in obese subjects contributing to the development of insulin resistance, type 2 diabetes, and cardiovascular diseases.This study investigated the inhibitory effect of an extract from bamboo Phyllostachys edulis (BEX) on lipotoxicity-induced over-production of IL-6 in metabolic cell lines.Palmitic acid (PA, 0.4 mM) was used to induce lipotoxicity in murine C2C 12, 3T3-L 1, and Hepa6 cells.Both intra-and extra-cellular protein concentrations of IL-6 were measured in the three cell lines after PA treatment with or without the presence of BEX using cytometric beads.
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