【摘 要】
：
A high quality reference genome is critical for understanding genetic variation and evolution of an organism.The long reads generated from single molecule,real-
【机 构】
：
StateKeyLaboratoryofPlantGenomics,InstituteofGeneticsandDevelopmentalBiology(IGDB),ChineseAcademyofS
【出 处】
：
2016年第三届全国功能基因组学学术峰会
论文部分内容阅读
A high quality reference genome is critical for understanding genetic variation and evolution of an organism.The long reads generated from single molecule,real-time (SMRT) sequencing technology have been used to assemble complete microbial genomes and high quality animal or plant draft genomes.However,for large eukaryotic genomes,especially plants,additional work is still required to obtain chromosome-scale continuity and to fix errors introduced by the assembly programs.Here we report the de novo assembly of an indica rice (Oryza sativa ssp.indica cultivar Shuhui498) genome by combining whole genome shotgun SMRT sequencing,fosmid library sequencing,genetic map construction and BioNano single-molecule mapping.
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