【摘 要】
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Due to the specific molecular recognization between bases,DNA has shown wonderful ability to create nanoscale structures from bottom up.With DNA it is possible to design and build two-and three-dimens
【机 构】
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Department of biological chemistry and molecular biology,Xi'an Jiaotong University,Xi'an,710061
【出 处】
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中国生物化学与分子生物学会2016年全国学术会议
论文部分内容阅读
Due to the specific molecular recognization between bases,DNA has shown wonderful ability to create nanoscale structures from bottom up.With DNA it is possible to design and build two-and three-dimensional shapes by self-assembly,and DNA nanostructures have shown promising applications in material organization and drug delivery.Because the shape of an object is determined by its angles,angle control strategy is the key to structure construction.I will describe the angle control strategies for DNA nanostructures with large molecular weight,which aims to construct more complex and lager structures with less DNA sequences.Currently,several methods to control the angles of DNA nanostructures have been investigated in our lab,and a series of n-point star nanostructures have been fabricated.I shall also describe the application of DNA nanostructures as drug carriers,especially the effects of their shapes and sizes on cellular uptake.
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