VERAPAMIL REDUCES TRANSMURAL DISPERSION OF REPOLARISATION AND PREVENTS TORSADE DE POINTES IN LQT2 MO

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户:serena_gy
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objectives To investigate the effects of verapamil on LQT2 models and its electrophysiologic mechanism by which verapamil suppresses torsades de pointes (TdP) in a developed left ventricular wedge model of LQT2.
其他文献
Objectives To investigate the potential beneficial effect of Bosentan in ameliorating fibrotic agents in diabetic mice.Methods Male C57BL/6 mice with 6-week old were divided into 3 groups (N =20) : Co
会议
Objectives Aortic valve interstitial cells (AVICs) play a vital role in the development of aortic valve stenosis.The aim of this study is to observe that whether or not AVICs calcified spontaneously a
会议
Objectives The purpose of this study was to compare two scoring systems used for diagnosis of acute mountain sickness (AMS): Lake Louise Scoring (AMS-LLS) and Chinese Scoring System (AMS-CSS).Methods
会议
Objectives CYP4F2 is responsible for metabolising arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), which plays a crucial role in the regulation of cardiovascular homeostasis.The present
会议
Objectives Superficial erosion of coronary plaques due to endothelial loss causes acute coronary syndromes (ACS).Hypochlorous acid (HOCl), a macrophages product can induce endothelial apoptosis.Distur
会议
Objectives Glycogen synthesis kinase-3β (GSK-3β) has been widely proved to be linked to the inhibition of the mPTP opening.This study aimed to determine whether puerarin prevents oxidative stress-indu
会议
Objectives Epidemiologic studies have been performed to explore the relationship between MCP-1 polymorphism and ischaemic heart disease (IHD) and ischaemic stroke (IS).But, the results are not consist
会议
Objectives Endothelial cell injury is a key event in the pathogenesis of atherosclerosis.There is now increasing evidence that excess lipid accumualtion can induce apoptosis which is thought to be tri
会议
Objectives Aortic valve interstitial cells (AVICs) play an vital role in the development of aortic valve stenosis.However, little progress is reported in isolation and culture of AVICs in rats,which i
会议
Objectives To investigate the effect of BH3 only protein Bim (Bcl-2 interacting the mediator of the cell death) on apoptosis induced by hypoxia in rat cardiomyocyte.Methods The Rat cardiomyocytes, 1-3
会议