论文部分内容阅读
近年来，具有阴离子跨膜转运活性的有机小分子化合物，因可望发展为“阴离子通道替代疗法”而成为药物化学和化学生物学领域的一个研究热点[1]。天然产物胆酸因其廉价易得和独特的两亲结构而成为构筑该类小分子化合物的一个重要骨架结构[2]。
二氨基胆酸二聚体的合成与阴离子跨膜转运活性
【摘 要】
：
近年来，具有阴离子跨膜转运活性的有机小分子化合物，因可望发展为“阴离子通道替代疗法”而成为药物化学和化学生物学领域的一个研究热点[1]。天然产物胆酸因其廉价易得和
【机 构】
：
南方医科大学药学院合成药物化学课题组广州510515
【出 处】
：
中国化学会全国第十二届有机合成化学学术研讨会
【发表日期】
：
2015年10期
其他文献
Some novel B-norcholesterol derivatives with thiazole ring were synthesized and their structures were characterized by IR,NMR and HRMS.The antiproliferative
会议
Water pollution is an environmental issue of world-wide focus.Removal of contaminants from water is a very important research area.Aniline and nitrobenzene
Domino reactions have received attention and h used as powerful tools in modern organic synthesis for the synthetically efficient construction of various he
Mitchellenes A-C,sesquiterpenes isolated by Davies and co-workers from the Eremophila mitchellii in 2011,1 havedisplayed moderate antiplasmodial inhibitory acti
会议
Amines are important structural motifs and intermediates for fine chemicals,pharmaceuticals,agrochemicals and natural products.Consequently,the development
In order to overcome the significant side effects and acquired or intrinsic resistance of platinum-based anticancer drugs,many efforts have been devoted to
Organic azide-alkene cycloadditions have been proven to be powerful synthetic tools for the ready access to diverse azaheterocycles in the past few decades.
揭示新颖的分子集群行为是开创新的学术生长点和新的学科分支的重要发端，也是了解微观分子自组织水平的重要媒介！尤其在有机合成方法学上所取得的众多创造性策略与复杂结构
呋喃类物质(如糠醛,5-羟基糠醛)是一类廉价可再生的资源型化合物,可通过生物质转化而来。另一方面,由于其芳香性较低,它们又是一种十分优良的C-5或者C-6的合成砌块,含有
Pine resin,a natural resin obtained from coniferous trees,exhibit some preferable biological activities such as anti-inflammatory,antiseptic and antioxidant