Neurotensin promotes the progression of malignant glioma cells through NTSR1 and affects prognosis o

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户：xiertimer

【摘要】

：

【作者】

：

LiangYi Xue-Yang Gong Hong-Juan Cui Lun-Shan Xu Min-Hui Xu

【机构】

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Department of Neurosurgery,Southwest Hospital,Third Military Medical University,Chongqing,China;Stat

【出处】

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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)

【发表日期】

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2013年7期

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Objective: Glioma is the most common and highly fatal intracranial malignant tumor characterized by resistance to alternating chemoradiation therapy and high recurrent rate after surgery and chemoradiation therapy, resulting in poor prognosis.Neurotensin (NTS), which is widely expressed in the central nervous system, causes the neuromodulator functions.Previous data indicated that the stimulation of NTS induces cellular proliferation and migration in various malignant tumors.

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