Regulatory axis of miR-195/497 and HMGA1/Id3 governs muscle cell proliferation and differentiation

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:shinboy_zsl
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Myocytes withdraw from the cell cycle to differentiation during muscle development.Given the capacity of microRNAs(miRNAs)regulating gene expression and during development,we screened for miRNAs that were muscle development-associated.Spoly(T)plus analysis of 273 miRNAs revealed 14 miRNAs were strongly upregulated with age of postnatal muscle development in vivo,including miR-195 and-497.
其他文献
Purpose: Women aged 40-49 are premenopausal.Epidemiological study shows that postmenopausal women are much more likely to have hypertension than ever.The prevalence among females is higher than that a
会议
Hypertension is characterized by overactive sympathetic nerve outflow.The rostral ventrolateral medulla(RVLM),containing presympathetic neurons,plays a key role in regulation of sympathetic tone and r
BACKGROUND AND OBJECTIVES: Alcoholic drinks have been consumed since thousands of years and the problems related to excess alcohol is present since then.It is a potent and dangerous drug of abuse and
会议
ASXL1 mutations are found in a spectrum of myeloid malignancies with poor prognosis.It is reported that Asxl1+/-mice develop myelodysplastic syndrome(MDS)-like or MDS and myeloproliferative neoplasms(
Background: Anemia is one of the commonest hematological ailment of infancy and childhood.Despite increased understanding of methods of detection and prevention the prevalence is very high.The diagnos
The proliferation,migration and inflammation of vascular smooth muscle cells(VSMCs)contributes to the pathogenesis and progression of several cardiovascular diseases such as atherosclerosis and hypert
The gating mechanisms of ion channels are normally revealed by single-channel kinetics analysis through readily monitored real-time electrophysiological recordings of interested ion channel [1].For so
Background: Epidural fibrosis has been demonstrated to be closely associated with poor surgical outcomes.Previous studies showed that taurine had remarkable anti-fibrotic effects on lung and liver fib
The present study aims to examine the role of an endogenous gasotransmitter,hydrogen sulfide(H2S),to regulate microRNA-192(miR-192)in promoting angiogenesis.Angiogenesis was measured in vitro(endothel
Objective: large-conductance calcium-activated potassium channels(BKCa)from vascular smooth muscle cells directly take part in the regulation of vasodilatation,and play a role in the maintenance of bl