Preparation of chiral stationary phases with thiol-ene click reaction of cellulose 3,5-dimethlypheny

来源 :Seventh International Symposium On Engineering Plastics (第七届 | 被引量 : 0次 | 上传用户:Holden
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The separation of enantiomers is demanded strongly in the biological, pharmaceutical and pesticide industries.Polysaccharide-based chiral stationary phases (CSPs), especially phenylcarbamate and benzoate esters of cellulose and amylose, are among the most efficient CSPs for HPLC, and nearly 90 % of chiral compounds can be successfully resolved1.However, the good solubility of polysaccharide derivatives in some of organic solvents limits the application range on the commercial chiral columns2.This problem can be solved by chemically immobilizing polysaccharide derivatives onto silica matrices.
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