【摘 要】
：
Aim To establish an animal model of laryngopharyngeal reflux (LPR) and study effect of LPR on the laryngopharyngeal mucosal ultrastructure.Methods Ten Bama minipigs were randomly divided into control
【机 构】
：
Department of Gastroenterology, Peking University People's Hospital,Beijing
【出 处】
：
The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议)
论文部分内容阅读
Aim To establish an animal model of laryngopharyngeal reflux (LPR) and study effect of LPR on the laryngopharyngeal mucosal ultrastructure.Methods Ten Bama minipigs were randomly divided into control group and stent group.Every pig underwent endoscope, baseline pH was monitored for 4 hours at the sites of laryngopharynx and distal esophagus, then specimens from laryngopharyngeal mucosa were biopsied.For the control group, these procedures were repeated on the 14th day.In the stent group, a custom-designed esophageal stent suit was implanted into esophagi, laryngopharyngeal and distal esophageal pH monitoring last for 2 hours, stent suit was removed 3 days later.On 14th day, the same procedures were conducted in the control group.Specimens were observed under transmission electron microscope to measure the intercellular space and desmosome number.
其他文献
Aims Identification of adherent-invasive Escherichia coli (AIEC) strains in IBD patients offers an opportunity to characterize the pathogenesis of microbial-induced intestinal inflammation.In which E.
Objective To investigate the correlation between special pathogens and colorectal adenomas (CRA) by comparing total bacteria, Bacteroides fragilis (BF), enterotoxigenic Bacteroides fragilis (ETBF), pk
Background and aim Information describing efficacy and safety of infliximab for Crohns disease (CD) in China is limited.The objective of this study was to report response rates, relapse rates after in
Objectives Increasing intestinal microbiota has been proposed as a basic pathogenic event in Crohns disease.Our aim was to study intestinal flora in active Crohns disease before and after treatment wi
Background Crohns disease (CD) is a chronic, relapsing, and debilitating idiopathic inflammation, with variable and complex pathophysiologies.Our objective was to elucidate patterns of gene expression
Objects The prevalence of Clostridium difficile infection in adults with inflammatory bowel disease (IBD) has not been well studied in China.This study was designed to investigate the cumulative incid
Background Incidence and mortality of intrahepatic cholangiocarcinoma (ICC) are increasing.However, its prognostic predictive system associated with outcome after surgery remains poorly defined.The pu
Objective This paper is aimed to explore psychological factors and life quality clinical characteristics of the functional dyspepsia patients with sleep disorders.Method According to the Pittsburgh Sl
Macrophages are key regulators of both innate and adaptive immunity, and essential for the initiation of pathogen recognition as well as their resolution due to their ability to induce inflammation, a
Objective To compare the inducing effect of different application options in mild-to-moderate ulcerative colitis.Methods One hundred eighty-six consecutive diagnosed ulcerative colitis cases from July