TBT is a kind of known endocrine disruptor,especially for resulting in the imposex in gastropods,but it is reported in some literature that it would result in masculinize.So we take the developing female Haliotis diversicolor in the period of early sexual development of gastropoda Prosobranchia as subjects,respectively pollute them,and determine the imposex level.Under the normal physiological conditions,the gonadal hormone level of Haliotis diversicolor changes as the reproductive periods,in control group,two of the gonad T and E2 levels are increased firstly and then decreased,the E2 level in hemolymph liquid is decreased firstly and then increased,but the ratio of T/E2 in sex gland keeps the same basically.The effect of TBT exposure on the level of sex gland T in Haliotis diversicolor is mainly embodied in late inducement by medium and high concentration pollution;for the low concentration group,the level of sex gland E2 is inhabited at the end of pollution period,for the medium concentration group,it is induced at the middle of pollution period,and for the high concentration group,it is inhibited all of the periods.From the view of histology,by electron microscope observation,large of the residuals are the residuals of brain yellow protein and the masculinize phenomena does not occur.