【摘 要】
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Respiratory behavior expresses diverse forms of plasticity by alterations in breathing patterns.Failure of respiratory plasticity often leads to diseases,such as sudden infant death syndrome or obstru
【机 构】
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Institute of Neurosciences, The Fourth Military Medical University, Xi'an, 710032, China
【出 处】
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中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
论文部分内容阅读
Respiratory behavior expresses diverse forms of plasticity by alterations in breathing patterns.Failure of respiratory plasticity often leads to diseases,such as sudden infant death syndrome or obstructive sleep apnea.Long-term facilitation (LTF) is the most frequently studied model for respiratory plasticity.Acute intermittent hypoxia (AIH),three to five short-term hypoxia episodes,induces phrenic LTF (pLTF),whereas chronic intermittent hypoxia (CIH),lasting for days or weeks stimulus episodes,evokes additional neuroplasticity and augmented pLTF.The previous studies,however,were mostly concentrated on phrenic neuroplasticity in high-cervical spinal cord.The pre-B(o)tzinger complex (pre-B(o)tC),a critical kernel of respiratory rhythmogenesis in the ventrolateral medulla oblongata,has been obscure until recently.
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