Objective Cancer cells are notorious for its strong plasticity in response to cytotoxic stress.They may modulate adaptive programs to survive during therapy.Upon lethal EGFR TKI exposure,drug-sensitiv
Objective Chromatin remodeling is known to play important roles in multiple physiological as well as pathological settings.Conserved from yeast to human,the SWI/SNF complex,as the essential components
Objective Radiation pneumonitis(RP)has long been well-known complication of patients undergoing thoracic radiation,which can lead to chronic respiratory insufficiency and seriously affect patients qua
Objective Background: Gastrectomy for treatment of patients with incurable advanced gastric cancer remains controversial.The objective of the present retrospective cohort study was to analyze whether
Objective The study was designed to test the hypothesis that halofuginone enhances treatment by improve bad tumor microenvironment caused by radiation,and try to explore the role of TGF-β in this prog
目的 腹腔镜肝切除目前已广泛应用于肝细胞癌病人的外科治疗中,总结我们中心开展的648 例腹腔镜肝切除,特别是大肝癌的腹腔镜肝切除,中央型肝癌的腹腔镜肝切除以及腹腔镜大范围肝切除的一些经验,探讨腹腔镜技术在肝细胞癌外科治疗中的安全性和可行性.方法 回顾性收集我们中心在2012 年1 月至2018 年6 月期间开展的648 例肝细胞癌腹腔镜肝切除术病人的临床资料,并与2012 年1 月至2016 年1
目的 分析影响良性、交界性及恶性粘液性卵巢肿瘤复发及预后的相关因素,为临床的诊治提供帮助.方法 回顾性分析2008 年1 月-2017 年12 月期间在河北医科大学第四医院收治的560 例粘液性卵巢肿瘤患者的临床病例资料,其中粘液性囊腺瘤患者368 例,粘液性卵巢交界性肿瘤(Mucinous borderline Ovarian tumors,MBOT)90 例,粘液性卵巢癌(mucinous e
Objective Myelodysplastic syndromes(MDS)comprise a heterogeneous group of hematopoietic stem cell disorders with ineffective hematopoiesis,cytopenias and a risk of progression to acute myeloid leukemi
Objective Hepatocellular carcinoma(HCC)is one of the most common malignancies and lethal neoplasm worldwide with rapidly increasing incidence.Sorafenib was firstly approved for the treatment of advanc
Objective To investigate the efficacy and safety of single-or double-drug cytotoxic regimens as second-line treatment of advanced gastric cancer,and to figure the potential predictive factors associat