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  5. Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxife

Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxife

来源 :第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 | 被引量 : 0次 | 上传用户：hyperpp
【摘 要】
：
Background: Acquired tamoxifen resistance(TamR)remains a major challenge in breast cancer endocrine therapy.The mechanism of acquiring tamoxifen resistance remains elusive,and no effective drugs are a
【作 者】
：
Zheyong Liang Wenjie Li Jie Liu Juan Li Fang He Yina Jiang Lu Yang Pingping Li Bo Wang Yaochun Wang Yu Ren Jin Yang Zhijun Luo CyrusVaziri Peijun Liu 
【机 构】
：
Center for Translational Medicine,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an
【出 处】
：
第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会
【发表日期】
：
2016年11期
【关键词】
：
simvastatin tamoxifen resistant breast cancer MCM7 RB 
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　　Background: Acquired tamoxifen resistance(TamR)remains a major challenge in breast cancer endocrine therapy.The mechanism of acquiring tamoxifen resistance remains elusive,and no effective drugs are available.
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