The treatment of bacterial infection is one of the most challenging tasks in the biomedical field [1].Antibiotics have been developed over 70 years and are regarded as the most efficient type of drug to treat bacterial infection [2].However,there is a concern that the over use of antibiotics can lead to a growing number of multidrug resistant bacteria.The development of new antibiotic delivery systems to improve the biodistribution and bioavailability of antibiotics is a practical strategy for reducing the generation of antibiotic-resistance and increasing the lifespan of newly developed antibiotics [3].