Cannabinoid and PPAR Receptors are Therapeutic Targets for the Treatment of Levodopa-induced Dyskine

来源 :中国上海第七届国际新药发明科技年会 | 被引量 : 0次 | 上传用户：hjwuser

【摘要】

：

【作者】

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Andrea Giuffrida

【机构】

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Department of Pharmacology University of Texas Health Science Center USA

【出处】

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中国上海第七届国际新药发明科技年会

【发表日期】

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2009年1期

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　　Long-term administration of L-3,4-dihydroxyphenilalanine (levodopa),the mainstay treatment for Parkinson s disease (PD),is accompanied by fluctuations in its duration of action and disabling motor complications termed dyskinesias.To date,no effective anti-dyskinetic treatments are available and there is a strong need for new pharmacological strategies.

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Cannabinoid and PPAR Receptors are Therapeutic Targets for the Treatment of Levodopa-induced Dyskine

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