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目的分析生物电阻抗法(MF-BIA)和双能X线吸收法(DXA)测量成年超重、肥胖人群骨矿含量的一致性,建立MF-BIA法校正预测模型,为MF-BIA法准确测量我国成年超重、肥胖人群的骨矿含量提供依据。方法志愿招募成年超重、肥胖者1323人,分别采用MF-BIA法和DXA法测定受试者的骨矿含量,分析2种方法测量结果的一致性,并建立MF-BIA法校正预测模型。结果 MF-BIA法测量成年超重男性、肥胖男性、超重女性、肥胖女性的骨矿含量与DXA法测量的骨矿含量差值分别为0.28、0.38、0.24和0.36 kg,差异均有统计学意义(P<0.05)。成年超重男性、肥胖男性、超重女性、肥胖女性MF-BIA法与DXA法测量骨矿含量的组内相关系数(ICC)分别为0.787、0.796、0.741和0.788,均有统计学意义(P<0.01)。MF-BIA法校正预测模型为:超重男性人群,骨矿含量(DXA法)=-0.297+1.005×骨矿含量(MF-BIA法);肥胖男性人群,骨矿含量(DXA法)=0.302+0.799×骨矿含量(MF-BIA法);超重女性人群,骨矿含量(DXA法)=0.780+0.598×骨矿含量(MF-BIA法);肥胖女性人群,骨矿含量(DXA法)=0.755+0.597×骨矿含量(MF-BIA法)。结论 MF-BIA法和DXA法测量中国成年超重、肥胖人群骨矿含量一致性较差;在中国成年超重、肥胖人群中,使用MFBIA法测量骨矿含量需进行校正。
OBJECTIVE: To analyze the consistency of bone mineral content in adult overweight and obese people by bioelectrical impedance spectroscopy (MF-BIA) and dual-energy X-ray absorptiometry (DXA), and to establish the MF-BIA corrected prediction model Our country adult overweight, obese people provide the basis for bone mineral content. Methods A total of 1,323 adult overweight and obese adults were recruited voluntarily. The bone mineral content of the subjects was measured by MF-BIA and DXA respectively. The consistency of the two methods was analyzed and the MF-BIA calibration model was established. Results The bone mineral content measured by MF-BIA in adult overweight males, obese men, overweight females and obese women was 0.28,0.38,0.24 and 0.36 kg, respectively, compared with those measured by DXA. The differences were statistically significant ( P <0.05). The intra-group correlation coefficients (ICC) of MF-BIA and DXA were 0.787,0.796,0.741 and 0.788 in adult overweight males, obese males, overweight females, and obese women, respectively, with statistical significance (P <0.01) ). MF-BIA method was used to correct the prediction model: overweight male population, bone mineral content (DXA method) = -0.297 + 1.005 × bone mineral content (MF-BIA method); bone mineral content (DXA method) = 0.302 + 0.799 × bone mineral content (MF-BIA method); overweight female population, bone mineral content (DXA method) = 0.780 + 0.598 × bone mineral content (MF- BIA method); obese female population, bone mineral content 0.755 + 0.597 × bone mineral content (MF-BIA method). Conclusion MF-BIA method and DXA method are not consistent in measuring bone mineral content in Chinese overweight and obese adults. In Chinese overweight and obese adults, the bone mineral content measured by MFBIA method should be corrected.