Designing Biomolecule Nanoscale Architectures for Therapeutics

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Cells rely on synergic functions of gene, protein and other biomolecules to maintain their normal activities; deliveries of such biomolecules hold the ultimate hope for many incurable diseases.The current technology for protein delivery can be grouped into two major directions: 1) protein encapsulation by assembling proteins with polymeric or amphiphilic molecules and, 2) protein-polymer conjugates by covalently linking protein with linear polymer chains or cell-penetrating peptides.
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