Nitric oxide inhibits 11,12-EET-induced porcine coronary arterial VSMCs hyperpolarization and relaxa

来源 :The 4th International Ion Channel Conference(第四届国际离子通道会议) | 被引量 : 0次 | 上传用户:menghuilong
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Aims: The vascular endothelial cells synthesize and release vasodilators such as Nitric oxide (NO) and epoxyeicosatrienoic acids (EETs).In normal physiological state, NO inhibits EETs mediated vascular relaxation.In this study, we tested the hypothesis that nitric oxide (NO) inhibits EETs and explored the mechanism of NO inhibition on EETs in isolated porcine small coronary arterial segments.
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