RIOK3 IS AN ADAPTOR PROTEIN REQUIRED FOR IRF3-MEDIATED ANTIVIRAL TYPE Ⅰ INTERFERON PRODUCTION

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：sitmaar

【摘要】

：

The innate immune response, such as production of type I interferons, acts as the first line of defense, limiting infectious pathogens directly and shaping the

【作者】

：

Jun Feng Paul D.De Jesus Victoria Su Stephanie Han Danyang Gong Nicholas C.Wu Yuan Tian Xudong Li Ting-Ting Wu Sumit K.Chand Ren Sun

【机构】

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DepartmentofMolecularandMedicalPharmacology,DavidGeffenSchoolofMedicine,UniversityofCaliforniaatLosA

【出处】

：

17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

：

2014年7期

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The innate immune response, such as production of type I interferons, acts as the first line of defense, limiting infectious pathogens directly and shaping the adaptive immune response.Detection of cytosolic nucleic acids by pattern recognition receptors leads to the induction of type I interferons.

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RIOK3 IS AN ADAPTOR PROTEIN REQUIRED FOR IRF3-MEDIATED ANTIVIRAL TYPE Ⅰ INTERFERON PRODUCTION

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