Identifying non-neoplastic cell populations in cancer hosts and investigating the roles of these cells in cancer progression, especially regarding their interac
CTL and NK cells mobilize their arsenal of effector molecules including FasL, granzymes, perforin and granulysin from lysosome-related storage vesicles.Followin
Effector cells of adaptive immunity express billions of clonally distributed antigen receptors.Since such a huge repertoire cannot be "stored" in each location
The adoptive transfer of ex vivo activated Natural Killer (NK) cells is a promising treatment option for patients suffering from different types of cancer in pa
The circadian clock regulates many cellular processes.Mitochondria play essential roles in metabolism, and are the major sites of reactive oxygen species (R
Objective: Alzheimers disease (AD) is the most common cause of cognitive impairment in older individual.Sleep disturbance is a risk factor of AD and can impair
Circadian clocks orchestrate daily oscillations in mammalian behaviors, physiology,and gene expression.It is reported that a considerable proportion of mRNA exp
The molecular mechanisms of how gravitational change affects circadian clock remains unclear.In this study, we investigated the effects and molecular mechan