论文部分内容阅读
Introduction: Cartilage oligomeric matrix protein (COMP) is a joint-specific arthritogenic antigen associated with rheumatoid arthritis and experimental arthritis animal model.We recently developed a mAb 1D10 recognizes the C-terminal globular domain of COMP and proved that mAb 1D10 is pathogenic.The present study was aimed to identify the antigenic epitope of monoclonal anti-cartilage oligomeric matrix protein antibody 1D10.