骨转换指标与骨质疏松性骨折风险评价

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户:yxhetao
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骨转换是新近认识的骨强度重要决定因素,它能影响骨质量构成的每个因素.骨转换过程可以通过生化标志反映出来,间接显示成骨细胞与破骨细胞的活性.骨转换指标是反映骨骼细胞活性与骨基质代谢水平的生化产物,通常分为骨形成标志物和骨吸收标志物两类,前者代表成骨细胞活性及骨形成状态,后者主要反应破骨细胞活性与骨吸收水平.
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伴随着人口老化的不断加剧,骨质疏松症已成为一个严重影响大众健康的问题而引起社会的广泛关注.据统计我国现有骨质疏松症患者约9千万人,骨量减少者约6千万人,每年因骨质疏松而导致骨折的发病率呈逐年上升的态势,给社会和家庭造成巨大的经济负担.因而预防和治疗骨质疏松性骨折就显得尤为重要.
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