【摘 要】
：
Gracilamine1 is a new member of the amaryllidaceae alkaloid family, and it can also be regarded as an aminal derivative of hydrofluorenone containing natural products (rings A-C).In this presentation,
【机 构】
：
Shanghai Key Laboratory of Green Chemistry and ChemicalProcesses, Department of Chemistry, East Chin
【出 处】
：
中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
Gracilamine1 is a new member of the amaryllidaceae alkaloid family, and it can also be regarded as an aminal derivative of hydrofluorenone containing natural products (rings A-C).In this presentation, we will introduce the total synthesis of gracilamine using three key ring-forming steps2:1) a mild photo-Nazarov reaction to form the B ring3, 2) 1,4-addition to form the D ring, and 3) intramolecular Mannich reaction to form the E ring.
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