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Basedon Sanyang Road combined railway and roadway river-cross shield tunnel in Wuhan, this paper has made a survey on negative influences on segment and unbind second lining in different conditions, including fire at the roadway region, fire at the railway region, and fire at both of the roadway and railway region.Temperature field distribution of lining and variety law of stress at high temperature are explored numerically through RABT heating curve of fire source.The results show that it doesn't make an interaction impact when two types of fires occur individually.Temperature of segment spandrel can reach about 650℃ due to be exposed to the fire directly.The other parts of segment are at a lower temperature due to the protection of unbind second lining.During the period of the fire, principal compressive stress of the segment makes any major changes with slight fluctuation, and maximum value distributes on the outside of segments.The principal compressive stress of unbind second lining increases first and then decreases.