【摘 要】
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The Drosophila fat body is an organ analogous to vertebrate adipose tissue and liver and functions as a major organ for nutrient storage and energy metaboli
【机 构】
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KeyLaboratoryofInsectDevelopmentalandEvolutionaryBiology,InstituteofPlantPhysiologyandEcology,Shangh
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The Drosophila fat body is an organ analogous to vertebrate adipose tissue and liver and functions as a major organ for nutrient storage and energy metabolism.It undergoes a distinct remodeling process,including autophagy,apoptosis,and cell dissociation,during the larval-pupal transition,which is mainly regulated by the steroid hormone (20-hydroxyecdysone,20E) and the sesquiterpenoid hormone (juvenile hormone,JH).We discovered: (1) The JH receptors MET and GCE mediate JH action to prevent 20E-induced apoptosis and cell dissociation.
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