【摘 要】
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Invasion,either directly or via metastasis formation,is the main cause of death in cancer patients,development of efficient anti-invasive agents is an important research challenge.Brartemicin is a tre
【机 构】
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Department of Pharmacology,School of Pharmaceutical Sciences,Shandong University,44 WestWenhuaRoad,J
【出 处】
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2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议
论文部分内容阅读
Invasion,either directly or via metastasis formation,is the main cause of death in cancer patients,development of efficient anti-invasive agents is an important research challenge.Brartemicin is a trehalose-based inhibitor of tumor cell invasion produced by the actinomycete of the genus Nonomuraea.DMBT (6,6-bis (2,3-dimethoxybenzoyl)-a,a-D-trehalose),one of brartemicin analogs,was found to be the most potent anti-invasive agent.The aim of this research is to explore the effects of DMBT on invasion and metastasis in B16BL6 cells.
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