【摘 要】
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Background: Acute pain is beneficial for the organism under dangerous conditions.However, chronic pain can be harmful to the body.Sickle cell disease (SCD) is a devastating genetic hemolytic disorder
【机 构】
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Biochemistry and Molecular Biology Department, University of Texas-Medical School, Houston,TX,USA;De
【出 处】
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中华医学会疼痛学分会第十一届学术年会
论文部分内容阅读
Background: Acute pain is beneficial for the organism under dangerous conditions.However, chronic pain can be harmful to the body.Sickle cell disease (SCD) is a devastating genetic hemolytic disorder associated with persistent chronic pain.Current strategies to manage pain suffer from a poor fundamental understanding of the molecular mechanisms underlying chronic pain.Although adenosine signaling is known for anti-pain in acute stage, nothing is known about its role in chronic pain.
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