Reduction of Drug Discovery cycle time is critical to the success of the Pharmaceutical Industry.In this talk, we will cover examples of the use of Flow Chemistry for the rapid production of compound libraries using a new, fully integrated synthesis and purification system,[1] a novel flow photochemical apparatus allowing high yield production of photochemically derived products[2] and also the use of novel Multicomponent Reactions for the production of unique pharmacologically relevant heterocycles for High Throughput screening campaigns.