Tibetan is considered to be a pristine and an ideal background site for atmospheric monitoring in the world [1].However,recent studies suggested that some pollutants have been long-range transported into Tibet and threatened the remote ecosystem.High levels of total mercury and methylmercury have been found in muscle of fish from rivers and lakes across the southern Tibet Plateau [2].However,the contamination status of the other trace metals in fish from the Tibetan Plateau were few studied and remains unclear.A total of thirty seven fish samples were collected from one lake(Nam Co Lake)and four rivers(Yarlung Zangbo River,Lhasa River,Salween and Niyang River)in Tibet.Concentrations of Cr,Mn,Co,Ni,Cu,As,Se,Cd and Pb were analyzed with an inductively coupled plasma mass spectrometer(ICP–MS)after microwave digestion.The concentrations were in the following ranges: Cr 0.39-3.20 mg/kg(average: 1.15 mg/kg),Mn 0.48-4.94 mg/kg(average: 1.45 mg/kg),Co 0.01-0.17 mg/kg(average: 0.03 mg/kg),Ni 0.02-8.18 mg/kg(average: 0.71 mg/kg),Cu 0.88-9.80 mg/kg(average: 2.54 mg/kg),As 0.05-2.85 mg/kg(average: 0.76 mg/kg)and Se 0.44-3.32 mg/kg(average: 1.32 mg/kg)based on a dry weight basis,respectively.Cd and Pb were not detected in all fish samples.Statistical analysis showed that weight,length,tropic level(TL)andδ13C influenced the metal concentrations in fish samples.For example,concentrations of Mn,Co and Cu had significantly negative correlation(p<0.05)with weight,TL andδ13C,respectively.Furthermore,contents of Mn had significantly positive correlation with the concentrations of Cr,Co and Ni(p< 0.05).Significant correlation had occurred between Cu-As-Se and Cu-As-Co(p< 0.05)as well.