The Relationship between Liver Leptin Expression and Liver Histological Changes in Patients with Chr

来源 :2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 | 被引量 : 0次 | 上传用户:littleshrimp1
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Chronic hepatitis C (CHC) is a kind of chronic liver diseases which is caused by hepatitis C virus (HCV) and complicated by cirrosis, cancer and fatty liver, etc.CHC is prone to fatty change of the liver compared with normal people.Leptin is a specific plasma protein of fatty tissue.There is hyperleptinemia in non-alcoholic fatty liver disease (NAFLD) patients.Leptin is the hot spot of research about NAFLD in recent years.The link between leptin and the degree of liverinjury and hepaticfibrosis is still disputable.The relationship between leptin and hepaic steatosis induced by HCV is not clear.
其他文献
Our knowledge of adipose tissue has changed from an inert energy storage tissue to an active endocrine organ, which communicates with central and peripheral organs through the synthesis and secretion
会议
Tamoxifen remains the first line therapy for estrogen receptor positive (ER+) breast cancer.However, polymorphisms of the gene encoding P450 2D6 could result in no protein expression or no CYP2D6 enzy
会议
Oxidative stress has been identified to play a causal role in insulin resistance.As a major endogenous anti-oxidative system, the function of nuclear factor-erythroid 2-related factor 2 (Nrf2) could b
会议
The ubiquitin-proteasome and autophagy-lysosome systems are major proteolytic pathways.Autophagy has recently emerged as an important regulatory pathway of lipid metabolism.Here, we investigated roles
会议
Obesity-induced chronic inflammation is deeply involved in insulin resistance, type 2 diabetes, and cardiovascular disease.A significant advance in our understanding of obesity-associated inflammation
会议
Acromegaly is a chronic and multisystemic disease having a high rate of morbidity and mortality due to cardiovascular, respiratory and metabolic causes.Although it is described an increase in benign a
会议
Breast cancer is the most common cancer in developed countries.In Singapore, age standardized rates (per 100,000/year) for breast cancer has risen almost three-fold from 20.0 to 58.5 per 100,000/year
会议
Traditional literature and textbooks generally describe that testosterone (T) is the main substrate for the biosynthesis of estradiol (E2), the most potent natural estrogen and dihydrotestosterone (DH
会议
As the prolactin receptor (PRLR) signaling was proved to be involved in breast and prostate tumorigenesis, there is a real need to develop therapeutic strategies to block its activation.The active com
会议
Deregulated expression of ER is found in 60% to 70% of breast tumors at the time of diagnosis indicating the relevance of ER expression with breast cancer progression.Emerging data also suggest that E
会议