【摘 要】
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Common metabolic alterations are associated with the progression of a growing number of neurodegenerative disorders, characterized by different ethiopatogenesis.In the case of adrenoleukodystrophy (X-
【机 构】
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University of Milan Italy
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Common metabolic alterations are associated with the progression of a growing number of neurodegenerative disorders, characterized by different ethiopatogenesis.In the case of adrenoleukodystrophy (X-ALD), an inherited demyelinating disorder, the mutated protein (ALDP) impair lipid catabolism.During the progression of this pathology, ALDP-related proteins can be overexpressed and partially compensate the lipid metabolic impairment.
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