A Stereoselective Synthesis of Fully Substituted Tetrahydrofurans through 1, 3-Dipolar Cycloaddition

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户：liongliong488

【摘要】

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【作者】

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Lin Qiu Xin Guo Shunying Liu Liping Yang Xiang Wu Wenhao Hu

【机构】

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Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development,East China N

【出处】

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The 24th International Society of Heterocyclic Chemistry Con

【发表日期】

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2013年4期

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An efficient mothed of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed.A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-ecnomic construction of highly substituted polycyclic chroman frameworks.

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A Stereoselective Synthesis of Fully Substituted Tetrahydrofurans through 1, 3-Dipolar Cycloaddition

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