Tumor necrosis factor receptor associated factor 5 is an essential mediator of ischemic brain infarc

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Background Tumor necrosis factor receptor-associated factor 5 (TRAF5) is an adaptor protein of the tumor necrosis factor (TNF) receptor superfamily and the interleukin-1 receptor/Toll-like receptor superfamily and plays important roles in regulating multiple signaling pathways.The role of TRAF5 in the context of brain ischemia/reperfusion injury has not yet been examined.
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