Genome editing of Lepidopteran model insect, Bombyx mori

来源 :The International Conference on Insect Molecular Ecology and | 被引量 : 0次 | 上传用户:wenruozhu
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  Silkworm belongs to Lepidoptera,an important economic insect,which could produce hundreds billions of dollars for Chinese agriculture and industry.In order to have further promotion of the silkworm influence,it is necessary to have new tools and targets for the purpose.In addition,silkworm works as a model of the 70%of agriculture and forestry pests,the progresses of silkworm research could be extended to these pests.Armed with genome information,transgenesis,and genome editing techniques,silkworm could get new chance for development in many aspects,such as genetic regulation,virus resistance and functional research.Furthermore,silkworm is considered as an ideal model for various researches of lepidopteran insects.In addition,with increasing demand for environmentally-friendly pest control,species specific gene targeting and genetic regulation are widely considered to be the future choice.Recently,the new technique of genome editing,offers us convenient alternatives for gene knock out and knock in.Using BmBlos2 gene as a target,both gene knock out and knock in strains were successfully created.These approaches are valuable as the screened target gene could be deleted,or a transgene sequence inserted in a target locus.
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