THE CHANGES OF FRAGILE HISTIDINE TRIAD GENE IN HEMATOLOGICAL SYSTEM OF MICE IN THE PROCESS OF RADIAT

来源 :第三届亚洲辐射研究大会 | 被引量 : 0次 | 上传用户:ggf9988998
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background: Radiation can cause tumorigenesis, with complex mechanism that has long been the research focus on oncology, radiobiology, and may be associated with oncogenes, cancer suppressor genes, and signal transduction.
其他文献
XRCC4-deficient (XRCC4-/-) cells generated by a gene targeting exhibit a lower survival rate and a higher frequency of chromosomal aberrations than parental HCT 116 cells after exposure to ionizing ra
Objective of this research was studying influence of various concentration of a dust of uranium ore (DUO) on animals in condition of lipid peroxidation (LP).
Associations of ionizing radiation (IR) and cancer risks in uranium mining and nuclear industry were published earlier.The action of high doses of IR also well investigated.
Although mutations and deletions of the p53 tumor suppressor gene lead to resistance to low linear energy transfer (LET) radiation, high LET radiation efficiently induces cell lethality and apoptosis
Induction of adaptive response (AR) by combination of irradiations with different LET values was attempted in a series of investigations in young adult female mice of C57BL/6J strain using mainly thir
Purpose/objectives: Normal lung tissue tolerance constitutes a limiting factor in delivering a required radiation dose.The biological effects of high precision particle therapy with protons or carbon
The lymphoid and myeloid lineage skewing potential is one of the characters of the aging hematopoietic stem cells(HSC).
会议
Non-phagocytic cell oxidase family of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is the major sources of reactive oxygen species(ROS)in a number of non-phygocyfic cells.
会议
Our previous study suggested that DNA-PKcs interacts with Snail1 which affect genomic instability, the sensitivity to DNA-damaging agents, and the migration of tumor cells by reciprocal regulation bet
The sources for cellular DNA damage include exposures to environmental chemicals and radiation as well as endogenous processes resulting from normal cellular metabolism.