EZH2/miRNA Axis Mediates Cancer Cell Proliferation, Survival,Invasivion and Cancer Stem Cell Mainten

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户：afraidboy

【摘要】

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【作者】

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Jun Yan Qing Zhang Wei Zhao Changxiao Ye

【机构】

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Model Animal Research Center Nanjing University China

【出处】

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2014第七届世界癌症大会

【发表日期】

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2014年12期

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　　EZH2, as a histone H3K27 methyltransferase, plays an essential role in regulation of cell proliferation,survival, invasiveness and cancer stem cell (CSC) maintenance.The upregulation of the histone methyltransferase EZH2 is frequently detected in various cancer types, including lung cancer and urinary bladder cancer (UBC).However, the mechanisms underlying its role in cancer cells have not yet fully understood.

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EZH2/miRNA Axis Mediates Cancer Cell Proliferation, Survival,Invasivion and Cancer Stem Cell Mainten

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