Dually responsive poly(ether urethane) nanoparticles as drug carriers for synergetic radio/chemother

来源 :第二届全球华人辐射研究大会 | 被引量 : 0次 | 上传用户:romotic
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The biodegradable temperature- and redox-responsive poly(ether urethane)s were synthesized for synergetic radio/chemotherapy.The amphiphilic poly(ether urethane)s were comprised of 2,2-dithiodiethanol,hydrophobic hexamethylene diisocyanate and hydrophilic poly(ethylene glycol) (PEG) segments,which was used to prepare cisplatin (CDDP)-loaded poly(ether urethane) nanoparticles.
其他文献
近年来,Toll类受体(Toll-like receptors,TLRs)及其激动剂在抗辐射损伤中的防治作用正引起放射生物学界的高度重视,2008年,受到美国国防部和NIH (national institutes of health)资助的Cleveland生物实验室在Science 杂志上报道其研究的改良型TLR5激动剂CBLB502(一种沙门氏菌毛蛋白)具有极强的辐射损伤防护效应,结果显示即
会议
The Nobel Prize 2011 went to Jules Hoffman and Bruce Beutler for their discoveries of Toll-like receptors (TLRs),while Albert Lasker Award for Basic Medical Research 2008 honored the discovery of micr
The heavy ion medical accelerator in Chiba (HIMAC) is the worlds leading heavy ion cancer treatment facility,and more than 8000 of patients with various radioresistant cancers were treated by HIMAC,an
会议
Passive beam delivery system including lateral beam shaping,range adjustment and modulation,and lateral field tailoring has been developed at the Institute of Modern Physics(IMP),Chinese Academy of Sc
会议
It has been known that genome instability exists in many cancers,and it may be a potential cause of tumorigenesis.Our studies demonstrated that genomic instability can be induced by ionizing radiation
Intense neutron generator based on D-D/D-T reaction plays an important role inthe following potential research fields,such as materials-damage studies,crosssection data measurement of key nuclides,tri
会议
Radiotherapy is an important lung cancer treatment modality.However,its efficacy is often compromised by the radioresistance of cancer cells and radiation-induced toxicity to normal lung tissue.TGF-β1
会议
Sedimentation of metals preserves the historicalrecord of contaminant input from local andregional sources,and can provide information on historical changes in regional water andsediment quality.High
Transuranium elements,especially plutonium,play a special role in advanced technological societies.However,owing to their radioactivity and toxicity,the related research is severely restricted.One of
会议
Among various imaging modalities,magnetic resonance (MR) imaging is one of the most widely applied and useful imaging techniques in the clinic.On the one hand,MR imaging can provide high spatial and t
会议