First successful preimplantation genetic diagnosis (PGD)of beta-thalassemia combined with HLA typing

来源 :中华医学会第七次全国生殖医学学术会议 | 被引量 : 0次 | 上传用户:runyran
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Objective To perform preimplantation genetic diagnosis (PGD) of beta-thalassemia combined with HLA typing for families designed to preselect unaffected embryos that were HLA antigen compatible with a sibling needing cord blood transplantation.Design & Method We investigated the use of multiple displacement amplification (MDA) from single cells as the first step for PGD.
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