【摘 要】
:
Objective To perform preimplantation genetic diagnosis (PGD) of beta-thalassemia combined with HLA typing for families designed to preselect unaffected embryos that were HLA antigen compatible with a
【机 构】
:
Center for Reproductive Medicine, Center for Reproductive Medicine, First Affiliated Hospital of Sun
【出 处】
:
中华医学会第七次全国生殖医学学术会议
论文部分内容阅读
Objective To perform preimplantation genetic diagnosis (PGD) of beta-thalassemia combined with HLA typing for families designed to preselect unaffected embryos that were HLA antigen compatible with a sibling needing cord blood transplantation.Design & Method We investigated the use of multiple displacement amplification (MDA) from single cells as the first step for PGD.
其他文献
胚胎成功植入受到宫腔病理学因素、子宫内膜厚度、凝血倾向和免疫等多种临床因素的影响,其中任何一个因素有缺陷均有可能导致胚胎植入失败.胚胎反复植入失败(repeatedimplantation failure,RIF)不仅对患者的身心造成了巨大打击而且加重了患者的经济负担,已成为辅助生殖技术中的一大困境.因此,我们必须积极探寻RIF的原因及应对策略,以改善IVF-ET的结局.
Backgroud Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders occurring to women.However, the relationship between hyperandrogensim and the clinical signs of androgen excess
Recently, several studies focused on the safety of fetus or offspring derived from assisted reproductive technology (ART) which might be suspected to result in more maternal and infant complications t
Objective Activin A was one of the altered expression cytokine, which up-regulated in the women with endometriosis.Investigation of Activin A in human endometrial stromal cells (ESCs) will explain the
Objective In previous study by microarray, we found that the e.xpression of SET gene was up-regulated in polycystic ovary syndrome (PCOS) ovaries.Some evidence suggested that SET gene was essential fo
Background The orphan nuclear receptor NR4A1 (NGFI-B/Nur77/TR3) is a member of the steroid hormone nuclear receptor superfamily with no identified endogenous ligand.NR4A1 is an immediately responding
Objective Placenta is a critical organ that protects the fetus and sustain pregnancy.Placenta hypoxia is related with many pregnancy complication.Tight junction (TJ) barrier is exit in placenta and pl
Objective To investigate the single nucleotide polymorphisms (SNPs) of tyrosine kinase domain of insulin receptor (INSR) gene in Chinese patients with polycystic ovary syndrome (PCOS).Patients 96 pati
Objective The human androgen receptor (AR) gene contains 2 polymorphic trinucleotide (CAG and GGN) repeats sequence in exon 1, which can transcript into Glutamine (Gln) and Glycine (Gly) respectively.
目的 比较体外受精-胚胎移植(IVF-ET)周期中GnRH拮抗剂与激动剂应用效果.方法 回顾性分析2006年11月~ 2007年6月在本中心接受IVF-ET助孕治疗的330例患者,其中采用GnRH拮抗剂方案的216例;采用GnRH激动剂长方案的114例患者,观察两组用药的临床效果.结果 两组Gn用量、HCG日内膜厚度、受精率、卵裂率之间比较无显著性差异;拮抗剂组种植率、妊娠率、活产率较激动剂组略高