The importance of GABA (Gamma Amino Butyric Acid) to health is well-documented.GABA is the main inhibitory neurotransmitter of the brain,and could be synthesized by the brain from glutamate or from glutamine.Most health claims of GABA supplements relate to effects in the brain,such as effects against depression,manic-depressive (bipolar) disorder,seizures,premenstual dysphoric disorder,anxiety and sleeping disorders,along with anti-pain effects,antihypertensive effect,etc.GABA from a fermented product has been suggested to have a blood pressure lowering effect on mildly hypertensive subjects.GABA is being sold as dietary supplement around the world with a plethora of health claims.Development of food with rich amount of GABA started in 80s in last century.Products containing GABA are mainly sold in food industry in Asia.In Japan,GABAhas been approved as FOSHU status.