【摘 要】
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The potential advantages of DNA-based molecular logic gates over traditional silicon based computers lie in their high flexibility,excellent biocompatibility,specific molecular recognization and predi
【机 构】
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School of Chemistry and Chemical Engineering,Yancheng Institute of Technology,Yancheng 224051
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The potential advantages of DNA-based molecular logic gates over traditional silicon based computers lie in their high flexibility,excellent biocompatibility,specific molecular recognization and predictable molecular behavior,which respond to unconventional identification signals such as chemicals,biomolecules,and light.[1] The design of such molecular logic gates is the possibility to connect logic units in complex circuits at the molecular level and has been investigated as a potential candidate for the development of DNA computer processor.Nowadays,the simultaneous multiplexed logical analysis to implement advanced logic operation is still a critical challenge for DNA computing and bioelectronics.Herein,an effective strategy in which multiplexed biomolecule inputs lighted up silver nanoclusters/MOFs was developed to construct a library of logic gates.We present a label-free,multiplexed,and fluorescent logic device based on single-stranded DNA templated silver nanoclustes(ssDNA-Ag NCs)[2] and Uio-66-NH2 nanocomposite.The Ag NCs/Uio-66-NH2 provides an instructive way for the integration of simultaneous multiple molecular devices and intelligent diagnosis.
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