The profile of T helper subsets in bone marrow microenvironment is distinct for different stages of

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户:shuangsssss
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objective The purpose of the current study was to illustrate the specific constitution and immune regulation mechanisms of Th subsets (especially the novel recognized Th17/Treg,Th9 and Th22 subsets) in BM environment of AML patients and to explore their roles in AML pathogenesis,progress and prognosis.Our study may offer a novel therapeutic target for treatment of AML.
其他文献
目的 美國從1995 年起就參考航空界的CRM(Crew Resource Management)訓練模式來進行不同醫療專業間的團隊訓練課程,以促進團隊合作,並將此手法運用於病人安全的相關議題上.醫策會於2008 年將CRM 引進台灣,將之定名為團隊資源管理(Team Resource Management,TRM),並於醫院間積極推廣.胸腔內科病房的住院病人平均年齡超過65 歲,跌倒是此年齡層住
会议
Objective This study was to investigate the effect of 5-Aza-2-deoxycytidine (decitabine;DAC)and all-trans retinoic acid (ATRA) on the expression of p16INK4a(p16) and retinoic acid receptor β(RARβ),as
会议
Introduction Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the Western countries (1).The diagnosis of CLL is based on presence of > 5 x109cells/L neoplastic B-cells in the
会议
Acute promyelocytic leukemia (APL) is characterized by the t(15;17)(q22;q21),which results in the fusion of th promyelocytic leukemia (PML) gene at 15q22 with the retinoic acid alpha-receptor(RARa) at
会议
Introduction A great majority of CLL p are elderly and with same grade of comorbidities.Recently,B as single agent showed superiority in comparison to Chlorambucil,with a good safety profile.Moreover,
会议
Objective Tyrosine kinase inhibitors (TKIs) have significantly improved the prognosis of Chronic myeloid leukaemia (CML) worldwide.Community-based data would be more reflective of the actual outcome a
会议
Objective The introduction of tyrosine kinase inhibitors (TKI) has changed the evolution and prognosis of Chronic Myeloid Leukaemia (CML) worldwide.However,the cost of TKIs is exorbitant and sometimes
会议
Similar to additional cytogenetic aberrations in patients with newly diagnosed chronic myelogenous leukemia-chronic phase (CML-CP),the clinical significance of chromosome abnormalities in patients wit
会议
Objective To explore the clinical and laboratory features of chronic myeloid leukemia (CML) with atypical e14a3 and e19a2 BCR-ABL fusion gene subtypes.Methods We retrospectively analyzed a cohort of C
会议
Objective The effects of emodin on growth inhibition and Akt pathway regulation were investigated in acute myeloid leukemia (AML) cells and AML xenograft models.Methods (1) Cell proliferation was meas
会议