【摘 要】
:
This study aims to investigate the oxidative stress and hepatocellular injury induced by the oral administration of Cr3+ in chicken.Different doses of CrCl3
【机 构】
:
CollegeofVeterinaryMedicine,ResearchCenterforAnimalDiseaseControlEngineeringShandongProvince,Shandon
【出 处】
:
中国畜牧兽医学会兽医内科与临床诊疗学分会第八届代表大会暨学术研讨会
论文部分内容阅读
This study aims to investigate the oxidative stress and hepatocellular injury induced by the oral administration of Cr3+ in chicken.Different doses of CrCl3 solutions (50% LD50, 25% LD50, and 12.5% LD50) and equivalent water were orally administered to Hylan Brown male chicken.Chicken liver samples were obtained every 2 weeks and measured the activities of antioxidant enzymes and the contents of glutathione, total antioxidant capacity, malondialdehyde, and hydrogen peroxide to indirectly evaluate the oxidative stress in chicken liver.Results indicated that the oral administration of Cr3+ at a high dose significantly increased (P<0.05) the MDA levels after 42 d of exposure.This observation was accompanied with the decrease in T-AOC, GSH and antioxidant enzymes activities.Similarity tendencies were observed when low and medium doses of Cr3+ long time were used.These statistics and histopathological analysis suggest that high-dose and long-term exposure of Cr3+ contributes to oxidative stress and hepatocellular injury.
其他文献
The one-third law introduced by Nowak et al.(Nature 428: 646-650, 2004) for the Moran stochastic process has proven to be a robust criterion to predict when
Single nucleotide polymorphisms (SNPs) are single base-pair substitutions that occur within and outside genes.They are the most common form of sequence variatio
综合分析了汾河源头管涔山地区的树轮宽度资料与该区域的气象干旱(降水),农业干旱(干旱指数)以及水文干旱(径流)之间的关系。相关分析表明,树轮宽度指数与三种干旱指数在
焦虑和恐惧是生物个体面临威胁性情境时的一种情绪性行为反应,它对于生物个体在复杂环境下的生存具有重要作用。已有研究表明,大脑杏仁核在动物个体的焦虑和恐惧反应中具有
人和野猪(Sus scrofa)的冲突已经成为日益关注的问题.2010年6月至2013年10月在黑龙江省哈尔滨市青云林场和吉林省珲春市,通过走访、问卷调查和实地考察研究了野猪的危害现
利用采自福建天宝岩的铁杉和台湾慈浪地区黄桧树轮样本,研制出树轮宽度年表,分析了其年表特征和气候响应特点。研究发现来自中国东南部地区的这两个树种的径向生长对气候的
Glutamine has a positive effect on ameliorating reproductive failure caused by porcine circovirus type 2 (PCV2).However, the mechanism by which glutamine af
运动是动物的基本特征,是动物生存的基础。运动也是人造系统完成其功能的重要前题。动物经过数十亿年的演化进化,获得了适应各种环境的优异的运动能力,激发了人类创新和学习
Disturbances directed at the maternal host during pregnancy can lead to direct physiological changes in the fetal environment and negatively affect the norm
Animals initiate different behaviors in respond to visual stimuli with distinct ecological meanings.Little is known about its underlying neural mechanisms a