AMPKα2 Deletion Exacerbates Neointima Hyperplasia via Skp2 Upregulation in Vascular Smooth Muscle Ce

来源 :BITs 2rd Annual World Cancer Congress of Cardiology-2010(201 | 被引量 : 0次 | 上传用户:haili20102010
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  Vascular smooth muscle cells (VSMC) proliferation plays a critical role in the development and progression of several vasculopathies.Adenosine monophosphate-activated protein kinase α (AMPKα) is reported to suppress cell proliferation of both tumor and epithelial cells.However, the role of isoform-specific AMPKα in vascular remodeling is unknown.
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