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目的分析小儿肺炎支原体肺炎(MPP)肺外并发症相关因素。方法选取2011年3月—2015年3月成都市金牛区中医医院儿科收治的MPP患儿92例,按是否合并肺外并发症分为并发症组53例与非并发症组39例。回顾性分析两组患儿年龄、性别、发热时间、肺炎支原体(MP)感染史、反复肺炎病史、喘息病史、过敏史、肺炎支原体抗体(MP-Ig M)滴度、大环内酯类药物使用时间、红细胞沉降率、C反应蛋白。结果两组患儿年龄≥2岁、发热时间≥7d、MP-Ig M滴度≥1∶160、7d内使用大环内酯类药物、红细胞沉降率、C反应蛋白水平比较,差异有统计学意义(P<0.05);年龄≥2岁、MP-Ig M滴度≥1∶160与肺外并发症呈中度相关(r年龄=0.425,rMP-Ig M滴度=0.418,P<0.05),发热时间≥7d、7d内使用大环内酯类药物与肺外并发症呈低度相关(r发热时间=0.300,r大环内酯类药物=0.268,P<0.05)。结论 MMP肺外并发症的发生率较高,年龄≥2岁、发热时间较长、MP-Ig M滴度高、C反应蛋白水平增高及红细胞沉降率加快的患儿应予以高度重视。
Objective To analyze the related factors of pulmonary complications of children with Mycoplasma pneumoniae pneumonia (MPP). Methods From March 2011 to March 2015, 92 children with MPP who were admitted to pediatric department of Jinniu District Chinese Medicine Hospital of Chengdu City were divided into 53 cases of complication group and 39 cases of non-complication group according to their complication or not. Retrospective analysis of two groups of children with age, gender, fever time, history of Mycoplasma pneumoniae infection, history of repeated pneumonia, history of wheezing, history of allergy, mycoplasma pneumoniae antibody (MP-Ig M) titer, macrolide Time of use, erythrocyte sedimentation rate, C-reactive protein Results The two groups of children aged ≥ 2 years old, fever time ≥ 7d, MP-Ig M titer ≥ 1: 160, 7d macrolide drugs, erythrocyte sedimentation rate, C-reactive protein levels, the difference was statistically significant (R = 0.425, rMP-Ig M titers = 0.418, P <0.05), and MP-Ig M titer≥1: 160 was associated with extrapulmonary complication , Fever time ≥7d, macrolides within 7d and pulmonary complications were low correlation (r fever time = 0.300, r macrolide = 0.268, P <0.05). Conclusions The incidence of extra-pulmonary complications is high, and children with age≥2 years, longer fever, high titer of MP-Ig M, elevated level of C-reactive protein and accelerated erythrocyte sedimentation rate should pay more attention.