【摘 要】
：
急性中耳炎(AOM)和复发性急性中耳炎(rAOM)是儿童常见耳疾之一,肺炎链球菌则是 AOM 和 rAOM 的最常见病原菌。本文研究青霉素 V(PcV)对肺炎链球菌性 AOM 的预防作用。35只雄
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急性中耳炎(AOM)和复发性急性中耳炎(rAOM)是儿童常见耳疾之一,肺炎链球菌则是 AOM 和 rAOM 的最常见病原菌。本文研究青霉素 V(PcV)对肺炎链球菌性 AOM 的预防作用。35只雄性 Sprague-Dawley 鼠(200～250g)在全麻下暴露双侧听泡,于耳显微镜下用一细针刺入右听泡注入浓度为6×10~7CFU/ml 的肺炎链球菌悬液0.05ml(接种耳),同法左听泡注入同量培养基悬液(对照耳)。15只
Acute otitis media (AOM) and recurrent acute otitis media (rAOM) are common childhood diseases, while S. pneumoniae is the most common pathogen of AOM and rAOM. This study was to investigate the preventive effect of penicillin V (PcV) against A pneumonia AOM. Thirty-five male Sprague-Dawley rats (200-250 g) were exposed bilaterally under general anesthesia, and a thin needle was inserted under ear microscopy to inject a suspension of S. pneumoniae suspended at a concentration of 6 × 10-7 CFU / ml Liquid 0.05ml (inoculation ear), the same method to listen to the same bubble into the medium medium suspension (control ear). 15 only
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