目的探讨妊娠合并碘缺乏病的筛选对胎儿结局的影响。方法选择2008年4月~2014年5月潍坊市益都中心医院参加孕期保健的孕妇635例,对所有孕妇的临床资料做问卷调查分析,其中问卷调查表为自制,妊娠在5~12周进行尿碘筛查和B超检测,检测胎儿的生长发育情况,同时观察胎儿是否有出现畸形现象,对于新生儿进行甲状腺功能和听力的筛查。结果经调查结果分析,妊娠合并碘缺乏病的患病几率为4.2%左右,其中农村患病率为4.4%,城镇患病率为3.8%;在本次研究的635例孕妇中,碘营养为正常的孕妇有604例,在这604例孕妇中所怀胎儿为不良结局的有83例,表现为胎儿异常比例为13.7%;有31例表现为碘缺乏的孕妇所怀的胎儿中有17例为不良结局,胎儿异常的发生率为54.8%。结论给妊娠早期的孕妇进行尿碘的筛查,尤其是甲状腺肿大的孕妇,同时应该检测甲状腺的功能,对于轻、中度碘缺乏的孕妇在怀孕期间要多补充富含碘的食品或改变饮食习惯,重度碘缺乏的孕妇需要服用对胎儿安全的补碘药物。 Objective To investigate the effect of pregnancy screening with iodine deficiency disorders on fetal outcomes. Methods From April 2008 to May 2014, Weidu Center Yidu Central Hospital, 635 pregnant women participated in the health care during pregnancy, all pregnant women do clinical survey data analysis, of which the questionnaire for the homemade pregnancy in 5 to 12 weeks Urinary iodine screening and B-test, detection of fetal growth and development, while observing the fetus whether there is deformity, thyroid function and hearing screening for newborns. Results According to the survey results, the prevalence of iodine deficiency disorders in pregnancy was about 4.2%, of which the prevalence in rural areas was 4.4% and that in urban areas was 3.8%. Among the 635 pregnant women in this study, iodine nutrition was There were 604 normal pregnancies, of whom 83 were pregnant with unwanted pregnancies in this 604 pregnant women, showing an abnormal fetal ratio of 13.7%; 31 of 31 pregnant women with iodine deficiency were pregnant The adverse outcome, the incidence of fetal abnormalities was 54.8%. Conclusions Urinary iodine screening for pregnant women in the first trimester of pregnancy, especially those with goiter, should be performed. The thyroid function should be examined. For pregnant women with light and moderate iodine deficiency, pregnant women should be supplemented with iodine-rich foods or changed Dietary habits, pregnant women with severe iodine deficiency need to take iodine supplements that are safe for the fetus.