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Acu-moxibustion therapy is one of the commonly-used remedies for the prevention and treatment of asthma. In the present article, the authors review development of clinical studies on acu-moxibustion treatment of asthma in recent 5 years from ① changes of pulmonary function as forced expiratory volume in 1second (FEV1), forced vital capacity (FVC), FEV1 %, peak expiratory flow (PEF), maximum mid expiratory flow (MMEF), etc., ② changes of immune function as serum IgE, IgG, subgroups of T lymphocytes, inflammatory mediators, cytokines, etc, and ③ changes of the nervous system and related receptors including nitric oxide (NO), vasoactive intestinal peptide (VIP), substance P (SP), and cAMP/cGMP. Additionally, the authors also introduce the development of experimental researches from the effects of acu-moxibustion on ①inflammatory cells, ② nervous system and receptors, ③ patho-morphological changes of the lung tissue, and④ serology of acupuncture.