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在皮肤科临床中,抗菌剂常与皮质激素合并外用治疗一些皮肤病,但抗菌剂的接触性过敏反应往往被忽视,使临床医生难以得知皮损不愈及加重之原因。作者于1980年1月至1983年12月,用各种能够得到的市售的局部使用的抗菌剂,其中包括呋喃西林、硫酸新霉素、土霉素、溴化十六烷基三甲铵、弗氏菌丝素、磺胺噻唑、Quiniodochlor,聚乙烯吡咯酮碘,吖啶黄,肝菌肽、红汞,硫酸庆大霉素、龙胆紫,盐酸洗必太、梭链孢酸钠等。对局部使用抗菌剂过敏的390例病人进行了常规斑贴试验。
In the dermatology clinic, antibacterials are often used in combination with corticosteroids to treat some skin diseases. However, the contact allergic reactions of the antibacterial agents are often neglected, making it difficult for the clinician to know the reasons why the skin lesions are unhealed and aggravating. The authors used various commercially available topical antibacterial agents available from January 1980 to December 1983, including nitrofurazone, neomycin sulfate, oxytetracycline, cetyltrimethylammonium bromide, Fusidin, Sulfathiazole, Quiniodochlor, Povidone, acridine yellow, pristin, Mercurochrome, gentamicin sulfate, gentian violet, chlorhexidine hydrochloride, fusidic sodium and so on. 390 patients locally allergic to antibacterials were given routine patch tests.